/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-B7-H3/CD276 Recombinant Monoclonal Antibody [BLR025F]
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Primary Antibodies  

Rabbit anti-B7-H3/CD276 Recombinant Monoclonal Antibody [BLR025F]

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

B7-H3/CD276

Reactivity:

Human

,

Mouse

Applications:

Flow Cyt

,

ICC

,

IHC

,

IHC-IF

,

IP

,

WB

Platforms:

COMET™

,

PhenoImager™ HT

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR025F

Format:

Whole IgG

Immunogen:

between 500 to 534 (C-term)

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (50+ tests)

10 µl (5+ tests)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


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Production Procedures

Recombinant antibody was purified from cell culture supernatant.

Immunogen was a peptide representing a region between residue 500 and the C-terminus (residue 534) of human CD276 Molecule using the numbering given in entry NP_001019907.1 (GeneID 80381).

Additional Product Information

CD276 may participate in the regulation of T-cell-mediated immune response. CD276 may play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. It may also be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces and could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5ZPR3].

80381

CD276

CD276 molecule

Q5ZPR3

CD276 antigen

Alternate Names

4Ig-B7-H3; B7 homolog 3; B7H3; B7-H3; B7RP-2; CD antigen CD276; CD276 antigen; costimulatory molecule

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.