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Rabbit anti-BCCIP IHC Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
BCCIP
Reactivity:
Human
Applications:
IHC
,IHC-IF
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 300 and 350
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Human
Antigen Species
Human
Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Production Procedures
Antibody was affinity purified using an epitope specific to BCCIP immobilized on solid support.
The epitope recognized by IHC-00636 maps to a region between residue 300 and 350 of human BRCA2 and CDKN1A interacting protein using the numbering given in entry NP_510868.1 (GeneID 56647).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to BCCIP immobilized on solid support.
The epitope recognized by IHC-00636-T maps to a region between residue 300 and 350 of human BRCA2 and CDKN1A interacting protein using the numbering given in entry NP_510868.1 (GeneID 56647).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
BCCIP (BRCA2 and CDKN1A interacting protein) was isolated as a BRCA2 and p21 interacting protein. Downregulation of BCCIP results in chromosome instability and incomplete cytokinesis indicating a role in DNA damage. Additionally, BCCIP is critical for BRCA2- and Rad51-dependent homologous recombinational repair.
Alternate Names
BCCIPalpha; BCCIPbeta; BRCA2 and CDKN1A-interacting protein; BRCA2 and Cip1/p21 interacting protein; cdk inhibitor p21 binding protein; p21- and CDK-associated protein 1; protein TOK-1; TOK1; TOK-1; TOK-1alpha; TOK-1beta
Applications
