Bethyl Laboratories
Rabbit anti-CC2D1A IHC Antibody Affinity Purified
Primary
Catalog #IHC-00414
TargetCC2D1A
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC, IHC-IF
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Product Description
CC2D1A functions as a transcriptional repressor of FRE (five repressor element) DNA element. As a repressor of this element, CC2D1A represses serotonin-1A receptor and dopamine-D2 receptor gene expression and has been linked to nonsyndromic mental retardation and psychiatric illnesses. The DNA binding and repressor activities of CC2D1A are regulated by the calcium-calmodulin-dependent protein kinase.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetCC2D1A
Antigen Species
Human
Gene ID54862
Gene Symbol
CC2D1A
Gene Name
coiled-coil and C2 domain containing 1A
Uniprot IDQ6P1N0
Protein Name
Coiled-coil and C2 domain-containing protein 1A
Alternate Names
Akt kinase-interacting protein 1 • coiled-coil and C2 domain-containing protein 1A • five prime repressor element under dual repression-binding protein 1 • five repressor element under dual repression-binding protein 1 • FRE under dual repression-binding protein 1 • FREUD-1 • Freud-1/Aki1 • MRT3 • putative NF-kappa-B-activating protein 023N • putative NFkB activating protein
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to CC2D1A immobilized on solid support.
The epitope recognized by IHC-00414 maps to a region between residues 1 and 50 of human Coiled-coil and C2 Domain Containing 1A using the numbering given in TrEMBL entry Q6P1N0 (GeneID 54862).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00414Open
Product DatasheetPDF · IHC-00414 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00414 · Lot 1 (current lot)Open
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