Rabbit anti-DDB1 IHC Antibody
Catalog #
DDB1
Human
,Mouse
IHC
Rabbit
Polyclonal
Whole IgG
Between 1100 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Guinea_pig,
Horse,
Monkey,
Dog,
Pig,
Rabbit,
X_laevis,
X_tropicalis,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development.
Alternate Names
damage-specific DNA binding protein 1, 127kDa; Damage-specific DNA-binding protein 1; DDB p127 subunit; DDBA; DNA damage-binding protein 1; DNA damage-binding protein a; HBV X-associated protein 1; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; UV-DDB 1; UV-DDB1; XAP1; XAP-1; xeroderma pigmentosum group E-complementing protein; XPCE; XPE; XPE-BF; XPE-binding factor
Applications