Bethyl Laboratories
Rabbit anti-hSET1 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00171
TargethSET1
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC
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Product Description
hSET1 is a subunit of a human Set1-like histone methyltransferase (HMT) complex. The Set-1 like complexes are responsible for mono-, di-, and tri-methylation of histone H3 K4. The Set class of proteins takes its name from the 130-140 aa motif SET domain identified in drosophila proteins. hSET1 associates with a multitude of proteins in a Set1-like complex which includes hSet1, Ash2L, RBBP5,WDR5, hDPY-30, hSwd2, CXXC1, and HCF1.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1200 and 1250
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargethSET1
Antigen Species
Human
Gene ID9739
Gene Symbol
SETD1A
Gene Name
SET domain containing 1A
Uniprot IDO15047
Protein Name
Histone-lysine N-methyltransferase SETD1A
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to hSET1 immobilized on solid support.
The epitope recognized by IHC-00171 maps to a region between residues 1200 and 1250 of human hSET1 (KIAA0339) using the numbering given in TrEMBL entry O15047 (GeneID 9739).
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00171Open
Product DatasheetPDF · IHC-00171 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00171 · Lot 1 (current lot)Open
Citations / Publications
Services
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