/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-LMTK2 Antibody
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Primary Antibodies  

Rabbit anti-LMTK2 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

LMTK2

Reactivity:

Human

Applications:

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 675 and 725

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Lemur tyrosine kinase (LMTK2) belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. LMTK2 interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. LMTK2 is involved in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggest an essential role of this protein in spermatogeness [taken from NCBI Entrez Gene (Gene ID: 22853)].

22853

LMTK2

lemur tyrosine kinase 2

Q8IWU2

Serine/threonine-protein kinase LMTK2

Alternate Names

AATYK2; apoptosis-associated tyrosine kinase 2; brain-enriched kinase; BREK; CDK5/p35-regulated kinase; cprk; cyclin-dependent kinase 5/p35-regulated kinase; hBREK; kinase/phosphatase/inhibitor 2; KPI2; KPI-2; Lemur tyrosine kinase 2; LMR2; PPP1R100; protein phosphatase 1, regulatory subunit 100; serine/threonine-protein kinase KPI-2; serine/threonine-protein kinase LMTK2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).