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Rabbit anti-RPSA Antibody

Bethyl Laboratories®

Bethyl Laboratories® Catalog #

Validated
Target:
RPSA
Reactivity:
Human, Mouse
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 245 and 295
IsoType:
IgG
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)

100 µl (10 blots)

20 µl (2 blots)

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Product Details

Specifications
Verified Reactivity
Mouse, Human
Presumed Reactivity
Zebrafish, Chicken, Rat
Antigen Species
Human
Stock Concentration
100 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
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Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
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Prod Procedures
Antibody was affinity purified using an epitope specific to RPSA immobilized on solid support.

The epitope recognized by A305-299A-T maps to a region between residue 245 to 295 of human 40S ribosomal protein SA using the numbering given in entry P08865.4 (GeneID 3921).

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Gene & Protein Information

RPSA is required for the assembly and/or stability of the 40S ribosomal subunit. RPSA is required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. RPSA also functions as a cell surface receptor for laminin and plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. RPSA may play a role in cell fate determination and tissue morphogenesis. It acts as a PPP1R16B-dependent substrate of PPP1CA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08865].

3921

RPSA

ribosomal protein SA

P08865

40S ribosomal protein SA

Alternate Names

37 kDa laminin receptor, 37 kDa laminin receptor precursor, 37/67 kDa laminin receptor, 37LRP, 40S ribosomal protein SA, 67 kDa laminin receptor, 67LR, colon carcinoma laminin-binding protein, ICAS, LAMBR, Laminin receptor 1, laminin receptor 1 (67kD, ribosomal protein SA), laminin-binding protein precursor p40, lamR, LAMR1, LBP, LBP/p40, LRP, LRP/LR, multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, p40, SA, small ribosomal subunit protein uS2

Applications

Western blot of immunoprecipitates performed using Normal Pig Serum (Cat. No. S100-020), Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) and 4-20% SDS-PAGE. Western blot of lysates performed using standard western blot reagents and 4-20% SDS-PAGE.