Rabbit anti-RSK2 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00683 maps to a region between residue 1 and 50 of human ribosomal S6 kinase 2 using the numbering given in entry NP_004577.1 (GeneID 6197).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to RSK2 immobilized on solid support.
The epitope recognized by IHC-00683-T maps to a region between residue 1 and 50 of human ribosomal S6 kinase 2 using the numbering given in entry NP_004577.1 (GeneID 6197).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Ribosomal protein S6 kinase alpha-2 (RSK2) is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. RSK2 kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signaling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome [taken from NCBI Entrez Gene (GeneID: 6197)].
Alternate Names
90 kDa ribosomal protein S6 kinase 3; CLS; epididymis secretory sperm binding protein; HU-3; insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK1B; MAPKAPK-1b; MRX19; p90-RSK 3; p90-RSK2; p90RSK3; pp90RSK2; ribosomal protein S6 kinase alpha-3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; ribosomal S6 kinase 2; RSK; RSK2; RSK-2; S6K-alpha3; S6K-alpha-3
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.