Bethyl Laboratories
Rabbit anti-SRPK2 IHC Antibody Affinity Purified
Primary
Catalog #IHC-00687
TargetSRPK2
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC, IHC-IF
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Product Description
Serine/arginine rich protein-specific kinase 2 (SRPK2) phosphorylates RS domain-containing proteins, such as SFRS1 and SFRS2 on serine residues. SRPK2 plays a role in spliceosome assembly and in mediating the trafficking of splicing factors. SRPK2 also appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P78362].
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 425 and 475
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetSRPK2
Antigen Species
Human
Gene ID6733
Gene Symbol
SRPK2
Gene Name
SRSF protein kinase 2
Uniprot IDP78362
Protein Name
SRSF protein kinase 2
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to SRPK2 immobilized on solid support.
The epitope recognized by IHC-00687 maps to a region between residue 425 and 475 of human SFRS protein kinase 2 using the numbering given in entry NP_872633.1 (GeneID 6733).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00687Open
Product DatasheetPDF · IHC-00687 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00687 · Lot 1 (current lot)Open
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