Rabbit anti-T-bet/TBX21 Recombinant Monoclonal Antibody [BLR110H]
Catalog #
T-bet/TBX21
Human
Flow Cyt
,ICC
,IHC
,IP
,WB
COMET™
,PhenoImager™ HT
Rabbit
Recombinant Monoclonal
BLR110H
Whole IgG
between 485 and 535 (C-term)
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
T-bet/TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX21 is a lineage-defining transcription factor which initiates Th1 lineage development from naive Th precursor cells both by activating Th1 genetic programs and activating transcription of a set of genes important for Th1 cell function, including those encoding IFN-gamma and the chemokine receptor CXCR3. [taken from NCBI Entrez Gene (Gene ID: 30009)].
Alternate Names
TBET; T-bet; TBLYM; T-box expressed in T cells; T-box protein 21; T-box transcription factor TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM
Applications