Mouse anti-CD74 Monoclonal Antibody, Purified [LN2]
Catalog #
CD74
Human
Flow Cyt
,ICC
,IHC
,WB
Mouse
Monoclonal
LN2
Whole IgG
human SU-DHL-4 lymphoma cells
IgG1
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
CD74 plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. CD74 also serves as cell surface receptor for the cytokine MIF. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P04233].
Alternate Names
CD antigen CD74; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule, major histocompatibility complex, class II invariant chain; DHLAG; gamma chain of class II antigens; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; Ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; II; MHC HLA-DR gamma chain; p33
Applications