Bethyl Laboratories
Rabbit anti-CREB IHC Antibody Affinity Purified
Primary
Catalog #IHC-00332
TargetCREB
HostRabbit
ClonalityPolyclonal
ReactivityMouse, Human
ApplicationIHC, IHC-IF
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Product Description
CREB (cyclic AMP response element-binding protein) is a ubiquitously expressed transcription factor that binds cAMP response elements to regulate gene transcription for various cellular responses such as glucose homeostasis, growth-factor dependent survival, and proliferation. CREB is also implicated to play a role in memory and mood.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 225 and 275
Isotype
IgG
Reactivity
Mouse, Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetCREB
Antigen Species
Human
Gene ID1385
Gene Symbol
CREB1
Gene Name
cAMP responsive element binding protein 1
Uniprot IDP16220
Protein Name
Cyclic AMP-responsive element-binding protein 1
Alternate Names
active transcription factor CREB • cAMP-response element-binding protein-1 • cAMP-responsive element-binding protein 1 • CREB • CREB-1 • cyclic adenosine 3',5'-monophosphate response element binding protein • cyclic adenosine 3',5'-monophosphate response element-binding protein CREB • cyclic AMP-responsive element-binding protein 1 • transactivator protein
Product Information
Applications
IHC, IHC-IF
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to CREB immobilized on solid support.
The epitope recognized by IHC-00332 maps to a region between residue 250 and 300 of human cAMP responsive element binding protein 1 using the numbering given in entry NP_604391.1 (GeneID 1385).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)1:50 - 1:500
Documents
Safety Data SheetPDF · IHC-00332Open
Product DatasheetPDF · IHC-00332 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00332 · Lot 1 (current lot)Open
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