Bethyl Laboratories
Rabbit anti-Paxillin IHC Antibody Affinity Purified
Primary
Catalog #IHC-00436
TargetPaxillin
HostRabbit
ClonalityPolyclonal
ReactivityHuman
ApplicationIHC
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Product Description
Paxillin functions as a signal transduction adaptor protein that localizes to focal adhesions and is involved in cell-adhesion and motility. Paxillin is a substrate of several protein kinases such as Src, FAK, and JNK. Serine and threonine phosphorylation of Paxillin appears to dictate its specific cellular activities.
Specifications
Clonality
Polyclonal
Host
Rabbit
Immunogen
Between 1 and 50
Isotype
IgG
Reactivity
Human
Format
Whole IgG
Conjugate Type
Unconjugated
Purity
Antigen Affinity Purified
Concentration
250 µg/ml
Target Identity
TargetPaxillin
Antigen Species
Human
Gene ID5829
Gene Symbol
PXN
Gene Name
paxillin
Uniprot IDP49023
Protein Name
Paxillin
Alternate Names
Product Information
Applications
IHC
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Storage Conditions
2 - 8 °C
Physical State
Liquid
Shelf Life
1 year from date of receipt
Country of Origin
USA
Production & Epitope
Antibody was affinity purified using an epitope specific to Paxillin immobilized on solid support.
The epitope recognized by IHC-00436 maps to a region between residues 1 and 50 of human Paxillin using the numbering given in Swiss-Prot entry P49023 (GeneID 5829).
Applications
Epitope exposure is recommended.
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.
Immunohistochemistry (IHC)1:100 - 1:500
Documents
Safety Data SheetPDF · IHC-00436Open
Product DatasheetPDF · IHC-00436 · Lot 1 (current lot)Open
Product DatasheetPDF · IHC-00436 · Lot 1 (current lot)Open
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