Rabbit anti-RFX5 Antibody Affinity Purified
Catalog #
RFX5
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 575 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Regulatory factor X-5 (RFX5) is a 75kDa subunit of the regulatory factor X (RFX) heteromeric complex that activates the transcription of major histocompatibility class II (MHC-II) genes by binding MHC-II promoter elements. The RFX complex consists of RFX5, RFXANK, and RFXAP. Mutations in these genes result in a lack of MHCII transcription and lead to the severe combined immunodeficiency disease, Bare Lymphocyte Syndrome (BLS).
Alternate Names
DNA-binding protein RFX5; regulatory factor X 5; regulatory factor X, 5 (influences HLA class II expression)
Applications