Rabbit anti-Fen1 Antibody Affinity Purified
Catalog #
Fen1
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
between 250 and 300
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Sheep,
Bovine
Human
2 - 8 °C
1 year from date of receipt
Flap endonuclease 1 (Fen1) is a member of the XPG/RAD2 endonuclease family. Fen1 functions primarily as an endonuclease that removes 5’-overhangs during base-excision DNA repair and lagging strand DNA synthesis. For these processes Fen1 interacts with PCNA and the 9-1-1 DNA repair complex. Fen1 also possesses 5’ to 3’ exonuclease activity as well as RNase H activity.
Alternate Names
DNase IV; FEN-1; flap endonuclease 1; Flap structure-specific endonuclease 1; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2
Applications