Rabbit anti-Bcl-xL Antibody
Catalog #
Bcl-xL
Human
WB
Rabbit
Polyclonal
Whole IgG
between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Pig,
Rat
Human
2 - 8 °C
1 year from date of receipt
Bcl-xL is part of the BCL-2 family of proteins that regulates apoptosis and cell cycle control. Bcl-xL is the protein product of the larger alternatively spliced isoform of Bcl-x. Bcl-xL functions similarly to BCL2 in promoting cell survival and inhibiting proliferation by promoting G0 arrest. Bcl-xL is located in the outer mitochondrial membrane and promotes cell survival by preventing mitochondrial release of cytochrome c and caspase activation in response to apoptotic signals.
Alternate Names
apoptosis regulator Bcl-X; BCL2L; Bcl2-L-1; bcl-2-like protein 1; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52
Applications