/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-TTK Antibody
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Primary Antibodies  

Rabbit anti-TTK Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (2)
Target:

TTK

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 800 and C-term

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

TTK is a cell-cycle regulated dual-specificity kinase that is part of the Mps1 family of kinases. TTK has been shown to interact with Chk2, a cell cycle checkpoint kinase, to mediate cellular responses to DNA damage. TTK has also been shown to be localized from the kinetochore to the centrosome at the entrance of anaphase, and required for mitotic spindle maintenance through the interaction with TACC2.

7272

TTK

TTK protein kinase

P33981

Dual specificity protein kinase TTK

Alternate Names

cancer/testis antigen 96; CT96; dual specificity protein kinase TTK; ESK; monopolar spindle 1 kinase; monopolar spindle 1-like 1; MPH1; MPS1; MPS1L1; phosphotyrosine picked threonine kinase; phosphotyrosine picked threonine-protein kinase; PYT

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.