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Rabbit anti-TRPM2 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

TRPM2

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 650 and 700

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Mouse

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

TRPM2 (transient receptor potential cation channel subfamily M member 2) is a voltage-independent cation channel that mediates susceptibility to cell death in response to oxidative stress. TRPM2 is activated by adenosine diphosphoribose (ADP-ribose) and its activation is dependent on calcium and calmodulin levels. A splice variant of TRPM2, TRPM2-S, has been shown to interact with the full length form and suppress calcium influx and susceptibility to cell death.

7226

TRPM2

transient receptor potential cation channel subfamily M member 2

O94759

Transient receptor potential cation channel subfamily M member 2

Alternate Names

EREG1; estrogen-responsive element-associated gene 1 protein; KNP3; long transient receptor potential channel 2; LTRPC2; LTrpC-2; NUDT9H; NUDT9L1; transient receptor potential cation channel subfamily M member 2; transient receptor potential channel 7; transient receptor potential melastatin 2; TRPC7

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.