Rabbit anti-DEC1 Antibody
Catalog #
DEC1
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
between 350 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
DEC1 is a basic helix-loop-helix transcription factor that appears to play a role in cell differentiation, proliferation, apoptosis, and the circadian rhythm. DEC1 is able to promote chondrogenic and osteogenic differentiation in mesenchymal stem cells by activating transcription of bone-related genes. When it is overexpressed in cells it can suppress apoptosis by blocking caspase activation and inducing transcription of survivin. DEC1 has also been found to play a role mammalian in circadian rhythm as a suppressor of the CLOCK/BMAL1 promoter.
Class E basic helix-loop-helix protein 40
Alternate Names
basic helix-loop-helix domain containing, class B, 2; BHLHB2; bHLHe40; class B basic helix-loop-helix protein 2; class E basic helix-loop-helix protein 40; Clast5; DEC1; differentially expressed in chondrocytes 1; differentially expressed in chondrocytes protein 1; differentiated embryo chondrocyte expressed gene 1; enhancer-of-split and hairy-related protein 2; HLHB2; SHARP2; SHARP-2; stimulated by retinoic acid gene 13 protein; STRA13; Stra14
Applications