Rabbit anti-SRA Antibody
Catalog #
SRA
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 180 and C-term
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Steroid receptor RNA activator 1 (SRA) was originally identified as a functional non-coding RNA that has been shown to be a coactivator of steroid receptors for androgens (AR), estrogens (ER), glucocorticoids, and progestins (PR). SRA exists in ribonucleoprotein complexes with steroid receptor coactivators (SRCs) and steroid receptors and may modulate transcriptional specificity. A 236 amino-acid protein encoded by an SRA-RNA isoform has also been identified. The SRA protein (SRAP) is widely expressed in breast cancer cell lines and breast cancer and has been demonstrated to modify the activity of the estrogen receptor.
Alternate Names
pp7684; SRA; SRAP; steroid receptor coactivator; steroid receptor RNA activator 1; steroid receptor RNA activator 1 (complexes with NCOA1); steroid receptor RNA activator protein; STRAA1
Applications