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Rabbit anti-Phospho MCM2 (S40/S41) Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
MCM2 Phospho (S40/S41)
Reactivity:
Human
Applications:
Flow Cyt
,IHC
,WB
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Surrounding serine 40/41
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (200 µg/ml)
10 µl (200 µg/ml)
Product Details
Specifications
Verified Reactivity
Human
Antigen Species
Human
Concentration
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Production Procedures
Antibody was affinity purified using an epitope specific to Phospho MCM2 (S40/S41) immobilized on solid support.
Immunogen was a synthetic di-phosphorylated peptide, which represented a portion of human minichromosomal maintenance deficient 2 surrounding Serines 40 and 41 according to the numbering given in entry NP_004517.2 (GeneID 4171).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to Phospho MCM2 (S40/S41) immobilized on solid support.
Immunogen for A300-788A-T was a synthetic di-phosphorylated peptide, which represented a portion of human minichromosomal maintenance deficient 2 surrounding Serines 40 and 41 according to the numbering given in entry NP_004517.2 (GeneID 4171).
Additional Product Information
The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM2 interacts with the core MCM complex (MCM4, 6, and 7) to regulate its helicase activity.
DNA replication licensing factor MCM2
Alternate Names
BM28; CCNL1; cdc19; CDCL1; cell devision cycle-like 1; cyclin-like 1; D3S3194; DFNA70; DNA replication licensing factor MCM2; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance protein 2 homolog; MITOTIN; nuclear protein BM28
Applications
