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Primary Antibodies  

Rabbit anti-PPP4C Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (23)
Target:

PPP4C

Reactivity:

Human

,

Mouse

Applications:

IHC

,

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1 and 50

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Presumed Reactivity

Rabbit,

Bovine,

Rat

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

PPP4C, also known as PPX, is the catalytic subunit of the PP4 serine/threonine protein phosphatase. PP4 is a holoenzyme that is comprised of the PPP4C catalytic subunit in association with the PP4-R1 or PP4-R2 regulatory subunits. PP4 has been demonstrated to directly interact with and activate NF-kappaB. PP4 also has been demonstrated to interact with histone deacetylase HDAC3 to influence transcription and to serve a role in microtubule organization during mitosis. Signaling through the MAPK and JNK-1 pathway has also been demonstrated to involve PP4.

5531

PPP4C

protein phosphatase 4 catalytic subunit

P60510

Serine/threonine-protein phosphatase 4 catalytic subunit

Alternate Names

epididymis secretory sperm binding protein; PP4; PP4C; PPH3; PPP4; PPX; PP-X; protein phosphatase 4 (formerly X), catalytic subunit; Protein phosphatase X; protein phosphatase X, catalytic subunit; serine/threonine-protein phosphatase 4 catalytic subunit

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.