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Rabbit anti-TCEB3 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

TCEB3

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 325 and 375

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

Transcription elongation factor B polypeptide 3 (TCEB3), also known as Elongin A, was identified as a factor that could increase the catalytic rate of Pol II transcription elongation. Transcription elongation is one step in the multistage process of transcription that involves the polymerization of nucleoside monophosphates into a ribonucleotide transcript catalyzed by Pol II. Successful elongation requires factors that promote sufficient elongation rates and processivity. TCEB3 or Elongin A is part of a heterotrimeric complex, Elongin (SIII) that includes Elongin A, B, and C and facilitates transcription elongation by suppressing transient pausing by Pol II.

6924

ELOA

elongin A

Q14241

Transcription elongation factor B polypeptide 3

Alternate Names

EloA; elongin 110 kDa subunit; elongin-A; RNA polymerase II transcription factor SIII subunit A1; SIII; SIII p110; TCEB3; TCEB3A; transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A); transcription elongation factor B alpha subunit; transcription elongation factor B polypeptide 3; transcription elongation factor B subunit 3

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.