Rabbit anti-PPP2R2B Antibody Affinity Purified
Catalog #
PPP2R2B
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 25 and 75
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Pig,
Rabbit,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
PP2A is a major serine/threonine phosphatase that is implicated in the negative control of cell cycle progression. It is a trimeric holoenzyme that is comprised of a catalytic, structural, and regulatory subunit. PPP2R2B is a regulatory subunit of PP2A. The regulatory subunits of PP2A are grouped into 3 families: B/PR55, B’/PR61, and B’’/PR72. PPP2R2B encodes a beta isoform of the B/PR55 subunit family. PPP2R2B is brain specific. An expansion of a CAG repeat in the 5’region of PP2R2B is associated with spinocerebellar ataxia type 12 (SCA12), an autosomal dominant neurodegenerative disorder.
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Alternate Names
B55BETA; PP2A subunit B isoform B55-beta; PP2A subunit B isoform beta; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform R2-beta; PP2A, subunit B, B-beta isoform; PP2AB55BETA; PP2ABBETA; PP2APR55B; PP2APR55BETA; PR2AB55BETA; PR2ABBETA; PR2APR55BETA; PR52B; PR55BETA; PR55-BETA; protein phosphatase 2, regulatory subunit B, beta; SCA12; serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, beta isoform; serine/threonine protein phosphatase 2A, neuronal isoform; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Applications