/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-GTF3C2/TFIIIC110 Antibody
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Primary Antibodies  

Rabbit anti-GTF3C2/TFIIIC110 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

GTF3C2/TFIIIC110

Reactivity:

Human

Applications:

IHC

,

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 75 and 125

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

General transcription factor 3C polypeptide 2 (GTF3C2/TFIIIC110) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C2/TFIIIC110 to the TFIIIC complex has not been fully determined. TFIIIC that is not associated with GTF3C2/TFIIIC110 has been purified, and it has been proposed that GTF3C2/TFIIIC110 functions to activate the TFIIIC complex for RNA polymerase III transcription. Recent studies argue against this model of GTF3C2/TFIIIC110 function.

2976

GTF3C2

general transcription factor IIIC subunit 2

Q8WUA4

General transcription factor 3C polypeptide 2

Alternate Names

general transcription factor 3C polypeptide 2; general transcription factor IIIC, polypeptide 2, beta 110kDa; TF3C-beta; TFIIIC 110 kDa subunit; TFIIIC110; TFIIIC-BETA; transcription factor IIIC 110 kDa subunit; transcription factor IIIC subunit beta

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.