Rabbit anti-TLK2 Antibody Affinity Purified
Catalog #
TLK2
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 722 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse
Human
2 - 8 °C
1 year from date of receipt
Tousled-like kinase 2 (TLK2) is a serine/threonine kinase involved in chromatin assembly and the DNA damage response. The tousled (Tsl) kinase was first identified in Arabidopsis thaliana and speculated to be involved in cell division during patterning of plant organs. There are two tousled-like kinases in humans, TLK1 and TLK2, that can dimerize or heterodimerize for function and can be phosphorylated and inactivated by Chk1 in response to DNA damage. The chromatin assembly factor, Asf1 (anti-silencing function 1), has been reported as a substrate for both TLK1 and TLK2.
Alternate Names
HsHPK; MRD57; PKU-ALPHA; serine/threonine-protein kinase tousled-like 2; Tousled-like kinase 2
Applications