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Rabbit anti-AKAP13/AKAP-Lbc Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

AKAP13/AKAP-Lbc

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 2754 and 2804

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

AKAP13/AKAP-Lbc was originally identified as an oncogenic protein that associates with the GTP-binding protein Rho. AKAP13-Lbc is also a member of the A-kinase anchoring protein family that functions as a molecular scaffold for the subcellular compartmentalization of A- kinase signaling molecules. AKAP13-Lbc has been found to possess Rho-specific guanine nucleotide exchange factor (GEF) activity and is critical to mediating RhoA activation and signal transduction.

11214

AKAP13

A-kinase anchoring protein 13

Q12802

A-kinase anchor protein 13

Alternate Names

A kinase (PRKA) anchor protein 13; AKAP-13; AKAP-Lbc; A-kinase anchor protein 13; ARHGEF13; breast cancer nuclear receptor-binding auxiliary protein; BRX; c-lbc; guanine nucleotide exchange factor Lbc; HA-3; Ht31; human thyroid-anchoring protein 31; LBC; LBC oncogene; lymphoid blast crisis oncogene; non-oncogenic Rho GTPase-specific GTP exchange factor; p47; PRKA13; protein kinase A-anchoring protein 13; PROTO-LB; PROTO-LBC

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.