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Rabbit anti-TReP-132/TRERF1 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

TReP-132/TRERF1

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 350 and 400

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

The transcriptional regulating protein of 132 kDa (TReP-132/TRERF1) was identified as a transcription factor that interacts with and activates the promoter of the CYP11A1 gene, a gene that encodes cytochrome P450 side chain cleavage (P450scc) and catalyzes the first step in steroidgenesis. TRep-132 can function as a nuclear receptor co-activator and has been shown to interact with Sp1 and the progesterone receptor (PR) to suppress growth via activation of the gene promoters of the cyclin-dependent kinase inhibitors, p21 and p27.

55809

TRERF1

transcriptional regulating factor 1

Q96PN7

Transcriptional-regulating factor 1

Alternate Names

BCAR2; breast cancer anti-estrogen resistance 2; dJ139D8.5; HSA277276; RAPA; rapa-1; rapa-2; transcriptional regulating protein 132; transcriptional-regulating factor 1; Transcriptional-regulating protein 132; TREP132; TReP-132; zinc finger protein rapa; zinc finger transcription factor TReP-132

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.