Rabbit anti-TReP-132/TRERF1 Antibody Affinity Purified
Catalog #
TReP-132/TRERF1
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 1150 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
The transcriptional regulating protein of 132 kDa (TReP-132/TRERF1) was identified as a transcription factor that interacts with and activates the promoter of the CYP11A1 gene, a gene that encodes cytochrome P450 side chain cleavage (P450scc) and catalyzes the first step in steroidgenesis. TRep-132 can function as a nuclear receptor co-activator and has been shown to interact with Sp1 and the progesterone receptor (PR) to suppress growth via activation of the gene promoters of the cyclin-dependent kinase inhibitors, p21 and p27.
Alternate Names
BCAR2; breast cancer anti-estrogen resistance 2; dJ139D8.5; HSA277276; RAPA; rapa-1; rapa-2; transcriptional regulating protein 132; transcriptional-regulating factor 1; Transcriptional-regulating protein 132; TREP132; TReP-132; zinc finger protein rapa; zinc finger transcription factor TReP-132
Applications