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Rabbit anti-AKAP9/CG-NAP Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

AKAP9/CG-NAP

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1075 and 1125

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

AKAP9/CG-NAP is a member of the A-kinase anchoring protein family that functions as a molecular scaffold for the subcellular compartmentalization of A- kinase signaling molecules. AKAP9/CG-NAP has been found to be critical to repolarization in the human heart. Defects in AKAP9/CG-NAP result in long QT syndrome type 11, a heart disorder characterized by ventricular arrhythmia and prolonged QT intervals. AKAP9/CG-NAP has been shown to form a multiprotein complex with the I(Ks) potassium channel subunit and play an essential role in its phosphorylation by PKA. AKAP9/CG-NAP is also important to centrosome and microtubule cytoskeletal organization.

10142

AKAP9

A-kinase anchoring protein 9

Q99996

A-kinase anchor protein 9

Alternate Names

A kinase (PRKA) anchor protein (yotiao) 9; A kinase (PRKA) anchor protein 9; AKAP 120-like protein; AKAP 350; AKAP 450; AKAP350; AKAP450; AKAP-9; AKAP9-BRAF fusion protein; A-kinase anchor protein 350 kDa; A-kinase anchor protein 450 kDa; A-kinase anchor protein 9; centrosome- and Golgi-localized PKN-associated protein; centrosome- and golgi-localized protein kinase N-associated protein; CG-NAP; hgAKAP 350; HYPERION; kinase N-associated protein; LQT11; MU-RMS-40.16A; PPP1R45; PRKA9; protein hyperion; protein kinase A anchoring protein 9; Protein kinase A-anchoring protein 9; protein phosphatase 1, regulatory subunit 45; protein yotiao; YOTIAO

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.