Rabbit anti-FBP17 Antibody Affinity Purified
Catalog #
FBP17
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 350 and 400
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Rat
Human
2 - 8 °C
1 year from date of receipt
FBP17 may act as a link between RND2 signaling and regulation of the actin cytoskeleton. FBP17 is required for the coordination of membrane tubulation and reorganization of the actin cytoskeleton during endocytosis. FBP17 binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. It also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. FBP17 may be required for the lysosomal retention of FASLG/FASL [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96RU3].
Alternate Names
FBP17; formin-binding protein 1; formin-binding protein 17; hFBP17
Applications