Rabbit anti-UBR1 Antibody Affinity Purified
Catalog #
UBR1
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 1125 and 1175
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
UBR1 is an E3 ubiquitin-protein ligase that is a component of the N-end rule pathway. UBR1 recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. UBR1 may be involved in pancreatic homeostasis. UBR1 binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8IWV7].
E3 ubiquitin-protein ligase UBR1
Alternate Names
E3 ubiquitin-protein ligase UBR1; E3a ligase; JBS; N-recognin-1; RING-type E3 ubiquitin transferase UBR1; ubiquitin ligase E3 alpha-I; ubiquitin-protein ligase E3-alpha; ubiquitin-protein ligase E3-alpha-1; ubiquitin-protein ligase E3-alpha-I
Applications