Rabbit anti-KCNMA1 Antibody Affinity Purified
Catalog #
KCNMA1
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 450 and 500
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Dog,
Chicken,
Pig,
Rabbit,
X. laevis,
Bovine,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
KCNMA1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1) is a potassium channel activated by both membrane depolarization or increase in cytosolic Ca2+ that mediates export of K+. KCNMA1 is also activated by the concentration of cytosolic Mg2+. Its activation dampens the excitatory events that elevate the cytosolic Ca2+ concentration and/or depolarize the cell membrane. KCNMA1 therefore contributes to repolarization of the membrane potential, and plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity.1, maxi K channel, MaxiK, Slo-alpha, slo1, slowpoke homolog, Slo homolog, and hSlo [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q12791].
Calcium-activated potassium channel subunit alpha-1
Alternate Names
bA205K10.1; big potassium channel alpha subunit; BK channel; BK channel alpha subunit; BKCA alpha; BKCA alpha subunit; BKTM; CADEDS; calcium-activated potassium channel subunit alpha-1; calcium-activated potassium channel, subfamily M subunit alpha-1; hSlo; k(VCA)alpha; KCa1.1; Maxi K channel; MaxiK; maxi-K channel HSLO; mSLO1; PNKD3; potassium channel, calcium activated large conductance subfamily M alpha, member 1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; SAKCA; SLO; slo homolog; SLO1; SLO-ALPHA; slowpoke homolog; stretch-activated Kca channel; uncharacterized protein
Applications