Rabbit anti-Toca-1 Antibody Affinity Purified
Catalog #
Toca-1
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
between 450 and 500
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Toca-1 is required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Toca-1 may bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Toca-1 also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5T0N5].
Alternate Names
C1orf39; formin-binding protein 1-like; TOCA1; toca-1; transducer of Cdc42-dependent actin assembly 1; transducer of Cdc42-dependent actin assembly protein 1
Applications