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Primary Antibodies  

Rabbit anti-CBFA2T3 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

CBFA2T3

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 603 and 653

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

CBFA2T3 (core-binding factor, runt domain, alpha subunit 2; translocated to, 3) is a member of the myeloid translocation gene family which interacts with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of the CBFA2T3 gene. This gene is also a putative breast tumor suppressor. [taken from NCBI Entrez Gene (Gene ID: 863)].

863

CBFA2T3

CBFA2/RUNX1 translocation partner 3

O75081

Protein CBFA2T3

Alternate Names

core-binding factor, runt domain, alpha subunit 2; translocated to, 3; ETO2; hMTG16; MTG16; MTG8-related gene 2; MTG8-related protein 2; MTGR2; myeloid translocation gene 8 and 16b; myeloid translocation gene on chromosome 16 protein; protein CBFA2T3; RUNX1T3; zinc finger MYND domain-containing protein 4; ZMYND4

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.