Rabbit anti-CBFA2T3 Antibody
Catalog #
CBFA2T3
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 603 and 653
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
CBFA2T3 (core-binding factor, runt domain, alpha subunit 2; translocated to, 3) is a member of the myeloid translocation gene family which interacts with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of the CBFA2T3 gene. This gene is also a putative breast tumor suppressor. [taken from NCBI Entrez Gene (Gene ID: 863)].
Alternate Names
core-binding factor, runt domain, alpha subunit 2; translocated to, 3; ETO2; hMTG16; MTG16; MTG8-related gene 2; MTG8-related protein 2; MTGR2; myeloid translocation gene 8 and 16b; myeloid translocation gene on chromosome 16 protein; protein CBFA2T3; RUNX1T3; zinc finger MYND domain-containing protein 4; ZMYND4
Applications