Rabbit anti-UBA6 Antibody
Catalog #
UBA6
Human
,Mouse
WB
Rabbit
Polyclonal
Whole IgG
Between 200 and 250
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
Ubiquitin-like modifier-activating enzyme 6 (UBA6) activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. UBA6 is specific for ubiquitin and does not activate ubiquitin-like peptides. UBA6 differs from UBE1 in its specificity for substrate E2 charging. UBA6 does not charge cell cycle E2s, such as CDC34. UBE6 is essential for embryonic development and required for UBD/FAT10 conjugation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/A0AVT1].
Ubiquitin-like modifier-activating enzyme 6
Alternate Names
E1-L2; monocyte protein 4; MOP-4; UBA6, ubiquitin-activating enzyme E1; UBE1L2; ubiquitin-activating enzyme 6; ubiquitin-activating enzyme E1-like 2; ubiquitin-activating enzyme E1-like protein 2; ubiquitin-like modifier-activating enzyme 6
Applications