Rabbit anti-PNP Antibody
Catalog #
PNP
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 239 and 289
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Purine nucleoside phosphorylase (PNP) is an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The PNP enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described [taken from NCBI Entrez Gene (Gene ID: 4860)].
Alternate Names
epididymis secretory sperm binding protein Li 156an; HEL-S-156an; inosine phosphorylase; inosine-guanosine phosphorylase; NP; PNP; PRO1837; PUNP; purine nucleoside phosphorylase; purine-nucleoside:orthophosphate ribosyltransferase
Applications