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Primary Antibodies

Rabbit anti-RLIP76 Antibody Affinity Purified

Name: Rabbit anti-RLIP76 Antibody
Brand: Bethyl Laboratories
SKU: A304-497A
Price: 121 USD

Bethyl Laboratories

Catalog #

Target:

RLIP76

Reactivity:

Human

Applications:

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 600 and 650

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications

Verified Reactivity

Human

Antigen Species

Human

Concentration

1000 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

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Additional Product Information

76 kDa Ral-interacting protein (RLIP76) can activate, specifically, hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RLIP76 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. It can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. It serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15311].

Gene ID:

10928

Gene Symbol:

RALBP1

Gene Name:

ralA binding protein 1

Uniprot ID:

Q15311

Protein Name:

RalA-binding protein 1

Alternate Names

76 kDa Ral-interacting protein; dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; ralA-binding protein 1; RalBP1; ral-interacting protein 1; RIP1; RLIP1; RLIP76

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.