Rabbit anti-BAG2 Antibody Affinity Purified
Catalog #
BAG2
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
BAG (Bcl-2-associated athanogene) proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner [taken from NCBI Entrez Gene (Gene ID: 9532)].
Alternate Names
BAG family molecular chaperone regulator 2; BAG-2; bcl-2-associated athanogene 2; dJ417I1.2; dJ417I1.2 (BAG-family molecular chaperone regulator 2)
Applications