Rabbit anti-SPG8/Strumpellin Antibody
Catalog #
SPG8/Strumpellin
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 1109 and 1159
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Zebrafish
Human
2 - 8 °C
1 year from date of receipt
SPG8/Strumpellin acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). SPG8/Strumpellin may be involved in axonal outgrowth [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q12768].
Alternate Names
KIAA0196; RTSC; RTSC1; SPG8; strumpellin; WASH complex subunit 5; WASH complex subunit strumpellin
Applications