Rabbit anti-VTA1/LIP5 Antibody Affinity Purified
Catalog #
VTA1/LIP5
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 257 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
VTA1 is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. VTA1 is thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. It is involved in the sorting and down-regulation of EGFR (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NP79].
Alternate Names
C6orf55; dopamine-responsive gene 1 protein; DRG1; DRG-1; homolog of mouse SKD1-binding protein 1; HSPC228; LIP5; LYST-interacting protein 5; My012; SBP1; SKD1-binding protein 1; vacuolar protein sorting-associated protein VTA1 homolog; vesicle (multivesicular body) trafficking 1; Vps20-associated 1 homolog
Applications