/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-PTPN2/TCPTP Antibody
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Primary Antibodies  

Rabbit anti-PTPN2/TCPTP Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

PTPN2/TCPTP

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 350 and 400

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Mouse,

Rat

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

The gene PTPN2, also known as TCPTP or TCP-TP, encodes for the protein tyrosine phosphatase (PTP) family member, tyrosine-protein phosphatase non-receptor type 2. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN2 dephosphorylates both receptor and non-receptor protein tyrosine kinases. PTPN2/TCPTP negatively regulates numerous signaling pathways and biological processes like hematopoiesis, inflammatory response, cell proliferation and differentiation, and glucose homeostasis [taken from NCBI Entrez Gene (Gene ID: 5771) and UniProtKB (Entry: P17706)].

5771

PTPN2

protein tyrosine phosphatase, non-receptor type 2

P17706

Tyrosine-protein phosphatase non-receptor type 2

Alternate Names

PTN2; PTPT; T-cell protein tyrosine phosphatase; T-cell protein-tyrosine phosphatase; TCELLPTP; TCPTP; TC-PTP; tyrosine-protein phosphatase non-receptor type 2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.