Rabbit anti-SPG20 Antibody Affinity Purified
Catalog #
SPG20
Human
IP
Rabbit
Polyclonal
Whole IgG
Between 500 and 550
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Bovine
Human
2 - 8 °C
1 year from date of receipt
Spastic paraplegia 20 protein (SPG20) is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Mutations associated with the SPG20 gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome) [taken from NCBI Entrez Gene (Gene ID: 23111)].
Alternate Names
spartin; spastic paraplegia 20 (Troyer syndrome); Spastic paraplegia 20 protein; SPG20; TAHCCP1; trans-activated by hepatitis C virus core protein 1
Applications