Rabbit anti-SNUPN Antibody
Catalog #
SNUPN
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 310 and 360
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. Snurportin-1 (SNUPN) interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor [taken from NCBI Entrez Gene (Gene ID: 10073)].
Alternate Names
KPNBL; RNA U transporter 1; RNUT1; Snurportin1; snurportin-1
Applications