/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-FLG2 Antibody
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Primary Antibodies  

Rabbit anti-FLG2 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (2)
Target:

FLG2

Reactivity:

Human

Applications:

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 100 and 150

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

The FLG2 protein is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. FLG2 is also required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa. [provided by RefSeq, Dec 2015] [taken from NCBI Entrez Gene (Gene ID: 388698)].

388698

FLG2

filaggrin family member 2

Q5D862

Filaggrin-2

Alternate Names

filaggrin-2; FLG-2; ifapsoriasin; IFPS; intermediate filament-associated and psoriasis susceptibility protein; Intermediate filament-associated and psoriasis-susceptibility protein; PSS6

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).