/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-Bcl6 Recombinant Monoclonal Antibody [BLR143H]
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Primary Antibodies  

Rabbit anti-Bcl6 Recombinant Monoclonal Antibody [BLR143H]

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

Bcl6

Reactivity:

Human

Applications:

Flow Cyt

,

ICC

,

IHC

,

IP

,

WB

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR143H

Format:

Whole IgG

Immunogen:

between 375 and 425

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (50+ tests)

10 µl (5+ tests)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


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Additional Product Information

Bcl6 is a zinc finger transcription factor and contains an N-terminal POZ domain. It acts as a sequence-specific repressor of transcription and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. Bcl6 can interact with a variety of POZ-containing proteins that function as transcription corepressors. Bcl6 is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL) and may be involved in the pathogenesis of DLCL. [taken from NCBI Entrez Gene (Gene ID: 604)].

604

BCL6

B cell CLL/lymphoma 6

P41182

B-cell lymphoma 6 protein

Alternate Names

B-cell lymphoma 5 protein; B-cell lymphoma 6 protein; B-cell lymphoma 6 protein transcript; BCL5; BCL-5; BCL-6; BCL6A; cys-his2 zinc finger transcription factor; LAZ3; lymphoma-associated zinc finger gene on chromosome 3; protein LAZ-3; ZBTB27; zinc finger and BTB domain-containing protein 27; zinc finger protein 51; zinc finger transcription factor BCL6S; ZNF51

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.