/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-CD103/ITGAE Recombinant Monoclonal Antibody [BLR171J]
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Primary Antibodies  

Rabbit anti-CD103/ITGAE Recombinant Monoclonal Antibody [BLR171J]

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

CD103/ITGAE

Reactivity:

Human

Applications:

ICC

,

IHC

,

IP

,

WB

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR171J

Format:

Whole IgG

Immunogen:

between 400 and 450

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (50+ tests)

10 µl (5+ tests)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


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Additional Product Information

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. CD103/ITGAE is an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, CD103/ITGAE forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen, and is preferentially expressed in human intestinal intraepithelial T-lymphocytes (IEL). In addition to a role in adhesion, CD103/ITGAE may serve as an accessory molecule for IEL activation. [taken from NCBI Entrez Gene (Gene ID: 3682)].

3682

ITGAE

integrin subunit alpha E

P38570

Integrin alpha-E

Alternate Names

alpha polypeptide; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD antigen CD103; CD103; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; HUMINAE; integrin alpha-E; integrin alpha-IEL; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1); mucosal lymphocyte 1 antigen

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.