/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-Hepassocin/FGL1 Recombinant Monoclonal Antibody [BLR210K]
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Primary Antibodies  

Rabbit anti-Hepassocin/FGL1 Recombinant Monoclonal Antibody [BLR210K]

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

Hepassocin/FGL1

Reactivity:

Human

Applications:

ICC

,

IHC

,

IP

,

WB

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR210K

Format:

Whole IgG

Immunogen:

residues 18-312 (full length)

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (50+ tests)

10 µl (5+ tests)

100 µg (BSA-Free)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
500 µg/ml 1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide


Request Formulation Change

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


Request Formulation Change
Additional Product Information

Hepassocin, also known as Fibrinogen-like 1 (FGL1), is a member of the fibrinogen family whose members share a fibrinogen domain at their C-termini. However, it lacks the platelet-binding site, cross-linking region and thrombin-sensitive site which are necessary for fibrin clot formation. Hepassocin/FGL1 is secreted by hepatocytes and may play a role in the development of hepatocellular carcinomas. Hepassocin/FGL1 is an immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 [taken from NCBI Entrez Gene (Gene ID: 2267)].

2267

FGL1

fibrinogen like 1

Q08830

Fibrinogen-like protein 1

Alternate Names

fibrinogen-like protein 1; hepassocin; hepatocellular carcinoma-related sequence; hepatocyte-derived fibrinogen-related protein 1; HFREP1; HFREP-1; HP-041; LFIRE1; LFIRE-1; liver fibrinogen-related protein 1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.