Rabbit anti-SIGLEC-15 Recombinant Monoclonal Antibody [BLR276L]

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

SIGLEC-15

Reactivity:

Human

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR276L

Format:

Whole IgG

Immunogen:

Between 278 and C-terminus

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (10 blots)

20 µl (2 blots)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


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Additional Product Information

SIGLEC-15 is a member of the SIGLEC family that binds sialylated glycoproteins. It is expressed on a subset of myeloid cells normally but is broadly upregulated on human cancer cells and tumor-infiltrating myeloid cells. SIGLEC-15 is suggested to be involved in the regulation of bone resorption and in osteoclast development. It has also been suggested to be involved in microbial infection and the cancer microenvironment. [taken from NCBI Entrez Gene (Gene ID: 284266)].

284266

SIGLEC15

sialic acid binding Ig like lectin 15

Q6ZMC9

Sialic acid-binding Ig-like lectin 15

Alternate Names

CD33 antigen-like 3;CD33 molecule-like 3;CD33L3;HsT1361;sialic acid-binding Ig-like lectin 15;SIGLEC-15

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).